Metastatic breast carcinoma to bone disguised by osteopoikilosis

J. G. Kennedy, J. R. Donahue, H. Aydin, B. H. Hoang, A. Huvos, C. Morris

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


A case of metastatic lobular carcinoma of the breast in conjunction with osteopoikilosis is described. Widespread diffuse sclerotic bone lesions were identified on radiographs in a patient with breast carcinoma. In addition computed tomography demonstrated discrete spherical areas of increased density throughout the skeleton manifest typically by osteopoikilosis. No systemic symptoms were evident, blood parameters were normal and the lesions did not demonstrate any increased uptake of technetium on bone scan. An iliac crest bone biopsy, however, revealed metastatic disease in addition to osteopoikilosis. Conventional radiological investigations may not delineate metastasis on a background of bone dysplasia.

Original languageEnglish (US)
Pages (from-to)240-243
Number of pages4
JournalSkeletal Radiology
Issue number4
StatePublished - Apr 1 2003
Externally publishedYes


  • Metastatic breast cancer
  • Osteopoikilosis
  • Radiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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