Metabolomics and bladder cancer

Matthew E. Hyndman; Jeffrey K. Mullins; Trinity J. Bivalacqua

doi:10.1016/j.urolonc.2011.05.014

Metabolomics and bladder cancer

Matthew E. Hyndman, Jeffrey K. Mullins, Trinity J. Bivalacqua

School of Medicine

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Diagnosis of bladder cancer is primarily made based on clinical presentation and then by direct visualization with cystoscopy. Despite the massive investments recently made to identify urinary-based assays that are able to diagnosis urothelial carcinoma, urine cytology and cystoscopy still remain the gold standard. Recently proof of principle studies have shown that noninvasive urine-based metabolomics, using high pressure liquid chromatography (HPLC) and nuclear magnetic resonance (NMR), may be able to accurately diagnosis bladder cancer. This review discuses the published studies investigating metabolomics and bladder cancer and the future potential of this developing field.

Original language	English (US)
Pages (from-to)	558-561
Number of pages	4
Journal	Urologic Oncology: Seminars and Original Investigations
Volume	29
Issue number	5
DOIs	https://doi.org/10.1016/j.urolonc.2011.05.014
State	Published - Sep 2011

Keywords

Bladder cancer
Cystoscopy
Cytology
Diagnosis
HPLC
Metabolomics
NMR
Review
Urine

ASJC Scopus subject areas

Oncology
Urology

Access to Document

10.1016/j.urolonc.2011.05.014

Cite this

@article{829f7368df7b40a1b67fc7cbb334946f,

title = "Metabolomics and bladder cancer",

abstract = "Diagnosis of bladder cancer is primarily made based on clinical presentation and then by direct visualization with cystoscopy. Despite the massive investments recently made to identify urinary-based assays that are able to diagnosis urothelial carcinoma, urine cytology and cystoscopy still remain the gold standard. Recently proof of principle studies have shown that noninvasive urine-based metabolomics, using high pressure liquid chromatography (HPLC) and nuclear magnetic resonance (NMR), may be able to accurately diagnosis bladder cancer. This review discuses the published studies investigating metabolomics and bladder cancer and the future potential of this developing field.",

keywords = "Bladder cancer, Cystoscopy, Cytology, Diagnosis, HPLC, Metabolomics, NMR, Review, Urine",

author = "Hyndman, {Matthew E.} and Mullins, {Jeffrey K.} and Bivalacqua, {Trinity J.}",

year = "2011",

month = sep,

doi = "10.1016/j.urolonc.2011.05.014",

language = "English (US)",

volume = "29",

pages = "558--561",

journal = "Urologic Oncology: Seminars and Original Investigations",

issn = "1078-1439",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Metabolomics and bladder cancer

AU - Hyndman, Matthew E.

AU - Mullins, Jeffrey K.

AU - Bivalacqua, Trinity J.

PY - 2011/9

Y1 - 2011/9

N2 - Diagnosis of bladder cancer is primarily made based on clinical presentation and then by direct visualization with cystoscopy. Despite the massive investments recently made to identify urinary-based assays that are able to diagnosis urothelial carcinoma, urine cytology and cystoscopy still remain the gold standard. Recently proof of principle studies have shown that noninvasive urine-based metabolomics, using high pressure liquid chromatography (HPLC) and nuclear magnetic resonance (NMR), may be able to accurately diagnosis bladder cancer. This review discuses the published studies investigating metabolomics and bladder cancer and the future potential of this developing field.

AB - Diagnosis of bladder cancer is primarily made based on clinical presentation and then by direct visualization with cystoscopy. Despite the massive investments recently made to identify urinary-based assays that are able to diagnosis urothelial carcinoma, urine cytology and cystoscopy still remain the gold standard. Recently proof of principle studies have shown that noninvasive urine-based metabolomics, using high pressure liquid chromatography (HPLC) and nuclear magnetic resonance (NMR), may be able to accurately diagnosis bladder cancer. This review discuses the published studies investigating metabolomics and bladder cancer and the future potential of this developing field.

KW - Bladder cancer

KW - Cystoscopy

KW - Cytology

KW - Diagnosis

KW - HPLC

KW - Metabolomics

KW - NMR

KW - Review

KW - Urine

UR - http://www.scopus.com/inward/record.url?scp=80052918426&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052918426&partnerID=8YFLogxK

U2 - 10.1016/j.urolonc.2011.05.014

DO - 10.1016/j.urolonc.2011.05.014

M3 - Review article

C2 - 21930087

AN - SCOPUS:80052918426

SN - 1078-1439

VL - 29

SP - 558

EP - 561

JO - Urologic Oncology: Seminars and Original Investigations

JF - Urologic Oncology: Seminars and Original Investigations

IS - 5

ER -

Metabolomics and bladder cancer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this