Abstract
Cell-based treatment represents a new generation in the evolution of biological therapeutics. A prototypic cell-based therapy, the mesenchymal stem cell, has successfully entered phase III pivotal trials for heart failure, signifying adequate enabling safety and efficacy data from phase I and II trials. Successful phase III trials can lead to approval of a new biological therapy for regenerative medicine.
Original language | English (US) |
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Pages (from-to) | 229-233 |
Number of pages | 5 |
Journal | Circulation Research |
Volume | 117 |
Issue number | 3 |
DOIs | |
State | Published - Jul 17 2015 |
Externally published | Yes |
Keywords
- cell- and tissue-based therapy
- chronic heart failure
- clinical trial
- heart disease
- mesenchymal stem cells
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine