Membranous aplasia cutis congenita: A recognizable lesion on prenatal sonography

A plasia cutis congenita (ACC) is a rare, etiologically heterogeneous condition characterized by the absence of a segment of skin. It usually presents as an isolated defect on the scalp slightly off the midline, but sometimes it may occur as multiple lesions.¹ It is typically a benign condition of potential cosmetic relevance but infrequently can be associated with major congenital anomalies. Several classification systems for ACC have been proposed. In 1986, Frieden² categorized ACC by the presence or absence of associated anomalies and the location and number of lesions. In addition to classification systems, subtypes of ACC have also been defined. Membranous ACC is a subtype of ACC that is generally diagnosed at birth by simple observation of a clean, sharply demarcated, and noninflammatory lesion of an area of skin similar to the lesion described in our case. This subtype is often associated with underlying neuroectodermal defects.