Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery

Kristen Nelson-McMillan, William J. Ravekes, William R. Thompson, Kristen M. Brown, Larry Wolff, Rajeev S. Wadia, Le Ann M. McNamara, Donald H. Shaffner, Ivor D. Berkowitz, Marshall L. Jacobs, Luca A. Vricella

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support. Oxygenator placement enabled transition to conventional ventilation and the discontinuation of vasopressor support. This case demonstrates the feasibility and safety of the use of this lung support system in patients requiring ventricular assist device (VAD) support.

Original languageEnglish (US)
Pages (from-to)105-109
Number of pages5
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Issue number1
StatePublished - Jan 1 2018


  • circulatory assist devices
  • heart failure
  • pediatric
  • pulmonary vascular resistance/hypertension

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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