TY - JOUR
T1 - Medical consequences of drug abuse and co-occurring infections
T2 - Research at the national institute on drug abuse
AU - Khalsa, Jag H.
AU - Treisman, Glenn
AU - McCance-Katz, Elinore
AU - Tedaldi, Ellen
PY - 2008/8/4
Y1 - 2008/8/4
N2 - Substance abuse still remains one of the major problems in the world today, with millions of people abusing legal and illegal drugs. In addition, a billion people may also be infected with one or more infections. Both drugs of abuse and infections are associated with enormous burden of social, economic, and health consequences. This article briefly discusses a few medical consequences of drugs of abuse and infections such as human immunodeficiency virus, hepatitis C virus, psychiatric complications in hepatitis C infection, pharmacokinetic drug-drug interactions among medications used in the treatment of addiction and infections, and new drugs in development for the treatment of infections. Research is encouraged to study interactions between infections, drugs of abuse, and underlying pathophysiologic and molecular/genetic mechanisms of these interactions.
AB - Substance abuse still remains one of the major problems in the world today, with millions of people abusing legal and illegal drugs. In addition, a billion people may also be infected with one or more infections. Both drugs of abuse and infections are associated with enormous burden of social, economic, and health consequences. This article briefly discusses a few medical consequences of drugs of abuse and infections such as human immunodeficiency virus, hepatitis C virus, psychiatric complications in hepatitis C infection, pharmacokinetic drug-drug interactions among medications used in the treatment of addiction and infections, and new drugs in development for the treatment of infections. Research is encouraged to study interactions between infections, drugs of abuse, and underlying pathophysiologic and molecular/genetic mechanisms of these interactions.
KW - Drug abuse
KW - Infections
KW - Medical consequences
UR - http://www.scopus.com/inward/record.url?scp=58149358829&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58149358829&partnerID=8YFLogxK
U2 - 10.1080/08897070802218661
DO - 10.1080/08897070802218661
M3 - Review article
C2 - 19042203
AN - SCOPUS:58149358829
SN - 0889-7077
VL - 29
SP - 5
EP - 16
JO - Substance Abuse
JF - Substance Abuse
IS - 3
ER -