Medical and surgical treatment of chronic venous ulcers

Michol A. Cooper, Umair Qazi, Eric Bass, Jonathan Zenilman, Gerald Lazarus, M. Frances Valle, Mahmoud B. Malas

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Venous ulcer of the lower extremity is a common vascular condition and is associated with decreased quality of life, reduced mobility, and social isolation. Treatment of chronic venous ulcer (CVU) includes compression therapy, debridement of the ulcer when necessary, and wound care. Collagen and antimicrobial dressings can improve the proportion of ulcers healed compared with compression alone. Acellular skin equivalents are not superior to compression, but cellular human skin equivalents can promote more rapid healing, particularly in patients with longstanding ulcers. Current vascular surgical practice is to eliminate documented reflux or obstruction in patients with CVU that have failed a 3-month period of compression dressing, debridement, and local wound care. We found that surgical treatment of the superficial venous system can decrease the time to healing of CVUs compared with compression therapy alone, but does not increase the proportion of ulcers healed.

Original languageEnglish (US)
Article number50489
Pages (from-to)160-164
Number of pages5
JournalSeminars in vascular surgery
Issue number3-4
StatePublished - Sep 1 2015

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine


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