Mechanisms of improvement following lung volume reduction surgery

Research output: Chapter in Book/Report/Conference proceedingChapter


In the earliest reports of lung volume reduction surgery (LVRS) for emphysema, Brantigan et al. (1) claimed short-term symptomatic benefits but reported no objective findings. They cited Laennec, who had speculated that a procedure that could diminish alveolar distension would lessen the problems of hyperinflation (2). Brantigan suggested three mechanisms to explain the improvement after LVRS: increased radial traction on the airways, restoration of more normal configuration of respiratory muscles, and increased recoil of the lung. Forty years of research have not proved Laennec was incorrect, but have expanded greatly on his speculations.

Original languageEnglish (US)
Title of host publicationLung Volume Reduction Surgery for Emphysema
PublisherCRC Press
Number of pages30
ISBN (Electronic)9780824757748
ISBN (Print)9780824708979
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Mechanisms of improvement following lung volume reduction surgery'. Together they form a unique fingerprint.

Cite this