Mechanism of Tumor Inhibition by Estrogen

Morton F. Goldberg, Abram Tregier, Milton S. Grossman

Research output: Contribution to journalArticlepeer-review


Immature AKD2F1 mice were examined for possible estrogenic inhibition of Sarcoma 1. Large doses of estradiol benzoate inhibited growth of tumor in intact animals and in hysterectomized castrates. It was concluded that this estrogenic effect can be achieved in absence of uterus, and that the tumor-inhibitory properties of endometrial secretions act by a mechanism different from that of estrogen.

Original languageEnglish (US)
Pages (from-to)408-410
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number2
StatePublished - Nov 1959
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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