Mechanism of cardioprotection: What can we learn from females?

Elizabeth Murphy; Claudia Lagranha; Anne Deschamps; Mark Kohr; Tiffany Nguyen; Renee Wong; Junhui Sun; Charles Steenbergen

doi:10.1007/s00246-010-9877-4

Mechanism of cardioprotection: What can we learn from females?

Elizabeth Murphy
, Claudia Lagranha
, Anne Deschamps
, Mark Kohr
, Tiffany Nguyen
, Renee Wong
, Junhui Sun
, Charles Steenbergen

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed.

Original language	English (US)
Pages (from-to)	354-359
Number of pages	6
Journal	Pediatric Cardiology
Volume	32
Issue number	3
DOIs	https://doi.org/10.1007/s00246-010-9877-4
State	Published - Mar 2011

Keywords

Cardioprotection
Estrogen signaling
G-protein-coupled receptor
Nuclear estrogen receptors

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Cardiology and Cardiovascular Medicine

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10.1007/s00246-010-9877-4

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title = "Mechanism of cardioprotection: What can we learn from females?",

abstract = "This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed.",

keywords = "Cardioprotection, Estrogen signaling, G-protein-coupled receptor, Nuclear estrogen receptors",

author = "Elizabeth Murphy and Claudia Lagranha and Anne Deschamps and Mark Kohr and Tiffany Nguyen and Renee Wong and Junhui Sun and Charles Steenbergen",

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AU - Murphy, Elizabeth

AU - Lagranha, Claudia

AU - Deschamps, Anne

AU - Kohr, Mark

AU - Nguyen, Tiffany

AU - Wong, Renee

AU - Sun, Junhui

AU - Steenbergen, Charles

PY - 2011/3

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N2 - This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed.

AB - This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed.

KW - Cardioprotection

KW - Estrogen signaling

KW - G-protein-coupled receptor

KW - Nuclear estrogen receptors

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UR - https://www.scopus.com/pages/publications/79953761440#tab=citedBy

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Mechanism of cardioprotection: What can we learn from females?

Abstract

Keywords

ASJC Scopus subject areas

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