TY - JOUR
T1 - Measurement of Spin-Lattice Relaxation Times in Systems Undergoing Chemical Exchange
AU - Horská, Alena
AU - Horský, Jiři
AU - Spencer, Richard G.S.
PY - 1994/1/1
Y1 - 1994/1/1
N2 - A new method is presented for measuring spin-lattice relaxation times in systems with chemical exchange. The method is based on an analysis of the effect of exchange on saturation factors. Unlike the inversion-recovery method with saturation, our experiment does not require selective excitation; it also does not require a fit of data to a multiple-exponential model, in contrast to inversion recovery without saturation. A number of variations of the experiment are presented, which are applicable to different regimes of T1 and exchange-rate values. The methods are demonstrated for the creatine kinase reaction in an in vitro sample.
AB - A new method is presented for measuring spin-lattice relaxation times in systems with chemical exchange. The method is based on an analysis of the effect of exchange on saturation factors. Unlike the inversion-recovery method with saturation, our experiment does not require selective excitation; it also does not require a fit of data to a multiple-exponential model, in contrast to inversion recovery without saturation. A number of variations of the experiment are presented, which are applicable to different regimes of T1 and exchange-rate values. The methods are demonstrated for the creatine kinase reaction in an in vitro sample.
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U2 - 10.1006/jmra.1994.1185
DO - 10.1006/jmra.1994.1185
M3 - Article
AN - SCOPUS:0002032833
SN - 1064-1858
VL - 110
SP - 82
EP - 89
JO - Journal of Magnetic Resonance - Series A
JF - Journal of Magnetic Resonance - Series A
IS - 1
ER -