Massive hepatic enlargement with fatty change associated with ketoconazole

J. D. Gradon; D. V. Sepkowitz

doi:10.1177/106002809002401206

Massive hepatic enlargement with fatty change associated with ketoconazole

J. D. Gradon, D. V. Sepkowitz

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Several forms of hepatic toxicity have been described with the antifungal agent ketoconazole. We report a case of massive liver enlargement with fatty infiltration presenting as gastric compression. This occurred in a young woman with AIDS taking ketoconazole as maintenance therapy for cryptococcal meningitis. This is the first reported case of ketoconazole causing fatty change in the liver.

Original language	English (US)
Pages (from-to)	1175-1176
Number of pages	2
Journal	DICP, Annals of Pharmacotherapy
Volume	24
Issue number	12
DOIs	https://doi.org/10.1177/106002809002401206
State	Published - 1990

ASJC Scopus subject areas

Pharmacology, Toxicology and Pharmaceutics(all)
Pharmacology (medical)

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title = "Massive hepatic enlargement with fatty change associated with ketoconazole",

abstract = "Several forms of hepatic toxicity have been described with the antifungal agent ketoconazole. We report a case of massive liver enlargement with fatty infiltration presenting as gastric compression. This occurred in a young woman with AIDS taking ketoconazole as maintenance therapy for cryptococcal meningitis. This is the first reported case of ketoconazole causing fatty change in the liver.",

author = "Gradon, {J. D.} and Sepkowitz, {D. V.}",

year = "1990",

doi = "10.1177/106002809002401206",

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AU - Gradon, J. D.

AU - Sepkowitz, D. V.

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AB - Several forms of hepatic toxicity have been described with the antifungal agent ketoconazole. We report a case of massive liver enlargement with fatty infiltration presenting as gastric compression. This occurred in a young woman with AIDS taking ketoconazole as maintenance therapy for cryptococcal meningitis. This is the first reported case of ketoconazole causing fatty change in the liver.

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JO - DICP, Annals of Pharmacotherapy

JF - DICP, Annals of Pharmacotherapy

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ER -

Massive hepatic enlargement with fatty change associated with ketoconazole

Abstract

ASJC Scopus subject areas

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