Marrow cell necrosis in anorexia nervosa and involuntary starvation

Robert R.L. Smith, Jerry L. Spivak

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Marrow specimens from six patients with anorexia nervosa and three with involuntary starvation were examined for the presence of gelatinous transformation and marrow cell necrosis. Five of the patients had pancytopenia. Acanthocytes were present in the circulation of all nine. In only two patients was marrow cellularity adequate. Gelatinous transformation was present in every marrow specimen and was of a marked degree in eight. Marrow cell necrosis was identified in all nine marrow specimens. The necrosis was extensive in one specimen, focal in the others and limited to the areas of gelatinous transformation. Severe malnutrition was the single element common to all the patients.

Original languageEnglish (US)
Pages (from-to)525-530
Number of pages6
JournalBritish journal of haematology
Issue number3
StatePublished - Jul 1985

ASJC Scopus subject areas

  • Hematology


Dive into the research topics of 'Marrow cell necrosis in anorexia nervosa and involuntary starvation'. Together they form a unique fingerprint.

Cite this