Mapping techniques for aligning sulci across multiple brains

Duygu Tosun, Maryam E. Rettmann, Jerry L. Prince

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


Visualization and mapping of function on the cortical surface is difficult because of its sulcal and gyral convolutions. Methods to unfold and flatten the cortical surface for visualization and measurement have been described in the literature. This makes visualization and measurement possible, but comparison across multiple subjects is still difficult because of the lack of a standard mapping technique. In this paper, we describe two methods that map each hemisphere of the cortex to a portion of a sphere in a standard way. To quantify how accurately the geometric features of the cortex - i.e., sulci and gyri - are mapped into the same location, sulcal alignment across multiple brains is analyzed, and probabilistic maps for different sulcal regions are generated to be used in automatic labelling of segmented sulcal regions.

Original languageEnglish (US)
Pages (from-to)295-309
Number of pages15
JournalMedical image analysis
Issue number3
StatePublished - Sep 2004


  • Brain
  • Conformal mapping
  • Cortex
  • Flattening
  • MRI
  • Mapping
  • Mean curvature
  • Partially flattened maps
  • Sulci labelling

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design


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