Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Hendrik P.N. Scholl; Andreas M. Schuster; Reinhard Vonthein; Eberhart Zrenner

doi:10.1016/S0042-6989(02)00034-2

Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Hendrik P.N. Scholl, Andreas M. Schuster, Reinhard Vonthein, Eberhart Zrenner

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.

Original language	English (US)
Pages (from-to)	1053-1061
Number of pages	9
Journal	Vision Research
Volume	42
Issue number	8
DOIs	https://doi.org/10.1016/S0042-6989(02)00034-2
State	Published - 2002
Externally published	Yes

Keywords

Best
Dystrophy
Electroretinogram (ERG)
Maculopathy
Multifocal

ASJC Scopus subject areas

Ophthalmology
Sensory Systems

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10.1016/S0042-6989(02)00034-2

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title = "Mapping of retinal function in Best macular dystrophy using multifocal electroretinography",

abstract = "In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.",

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T1 - Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

AU - Scholl, Hendrik P.N.

AU - Schuster, Andreas M.

AU - Vonthein, Reinhard

AU - Zrenner, Eberhart

PY - 2002

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AB - In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.

KW - Best

KW - Dystrophy

KW - Electroretinogram (ERG)

KW - Maculopathy

KW - Multifocal

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Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Abstract

Keywords

ASJC Scopus subject areas

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