Management of injuries caused by cryptococcus neoformans-contaminated needles

Arturo Casadevall, Jean Mukherjee, Rui Rong Yuan, John Perfect

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


This report describes four skin-puncture accidents with needles that were heavily contaminated with Cryptococcus neoformans. In one accident, delayed administration of antifungal drugs resulted in a granuloma of the finger. In the other three accidents, no skin infection followed immediate prophylaxis with oral fluconazole. Our experience suggests that early therapy with fluconazole is a reasonable means of managing skin injuries caused by instruments contaminated with viable C. neoformans.

Original languageEnglish (US)
Pages (from-to)951-953
Number of pages3
JournalClinical Infectious Diseases
Issue number5
StatePublished - Nov 1994
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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