Male circumcision and the risk of sexually transmitted infections and HIV in Rakai, Uganda

Ronald Gray; Jim Azire; David Serwadda; Noah Kiwanuka; Godfrey Kigozi; Bmohamed Kiddugavu; Fred Nalugoda; Xianbin Li; Maria Wawer

Male circumcision and the risk of sexually transmitted infections and HIV in Rakai, Uganda

Ronald Gray, Jim Azire, David Serwadda, Noah Kiwanuka, Godfrey Kigozi, Bmohamed Kiddugavu, Fred Nalugoda, Xianbin Li, Maria Wawer

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

We assessed the prevalence of sexually transmitted infections (STIs) caused by gonorrhea, chlamydia, syphilis and herpes simplex virus 2, genital ulcer disease and discharge/dysuria, and the incidence of HIV in circumcised and uncircumcised men in a Ugandan cohort study. There were no significant differences in the prevalence of STIs or genitourinary symptoms, but HIV incidence was significantly lower in circumcised men. The preputial mucosa is probably an important target tissue for HIV, but not other STIs.

Original language	English (US)
Pages (from-to)	2428-2430
Number of pages	3
Journal	AIDS
Volume	18
Issue number	18
State	Published - Dec 3 2004

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

Cite this

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AU - Azire, Jim

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AU - Kigozi, Godfrey

AU - Kiddugavu, Bmohamed

AU - Nalugoda, Fred

AU - Li, Xianbin

AU - Wawer, Maria

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AB - We assessed the prevalence of sexually transmitted infections (STIs) caused by gonorrhea, chlamydia, syphilis and herpes simplex virus 2, genital ulcer disease and discharge/dysuria, and the incidence of HIV in circumcised and uncircumcised men in a Ugandan cohort study. There were no significant differences in the prevalence of STIs or genitourinary symptoms, but HIV incidence was significantly lower in circumcised men. The preputial mucosa is probably an important target tissue for HIV, but not other STIs.

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Male circumcision and the risk of sexually transmitted infections and HIV in Rakai, Uganda

Abstract

ASJC Scopus subject areas

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