TY - JOUR
T1 - Make your own cigarettes
T2 - Toxicant exposure, smoking topography, and subjective effects
AU - Koszowski, Bartosz
AU - Rosenberry, Zachary R.
AU - Viray, Lauren C.
AU - Potts, Jennifer L.
AU - Pickworth, Wallace B.
N1 - Publisher Copyright:
© 2014 AACR.
PY - 2014/9/1
Y1 - 2014/9/1
N2 - Methods: In a laboratory study, we compared two types of MYO cigarettes-roll your own (RYO) and personal machine made (PMM)-with factory-made (FM) cigarettes in three groups of smokers who exclusively used RYO (n = 34), PMM (n = 23), or FM (n = 20). Within each group, cigarettes were smoked in three conditions: (i) after confirmed overnight tobacco abstinence; (ii) in an intense smoking paradigm; and (iii) without restrictions. All cigarettes were smoked ad lib through a smoking topography unit.Background: Despite considerable use of make your own (MYO) cigarettes worldwide and increasing use in the United States relatively little is known about how these cigarettes are smoked and the resultant toxicant exposure.Results: Plasma nicotine significantly increased after cigarettes in all conditions except PMM in the intense smoking paradigm. Puff volume, puff duration, total puff volume, and puff velocity did not differ between cigarette types but the puffs per cigarette and time to smoke were significantly smaller for RYO compared with PMM and FM. Regardless of the cigarette, participants consumed the first three puffs more vigorously than the last three puffs.Conclusions: Despite the belief of many of their consumers, smoking MYO cigarettes is not a safe alternative to FM cigarettes. Like FM, MYO cigarettes expose their users to harmful constituents of tobacco smoke. Despite differences in size and design their puffing profiles are remarkably similar.Impact: These data are relevant to health and regulatory considerations on the MYO cigarettes.
AB - Methods: In a laboratory study, we compared two types of MYO cigarettes-roll your own (RYO) and personal machine made (PMM)-with factory-made (FM) cigarettes in three groups of smokers who exclusively used RYO (n = 34), PMM (n = 23), or FM (n = 20). Within each group, cigarettes were smoked in three conditions: (i) after confirmed overnight tobacco abstinence; (ii) in an intense smoking paradigm; and (iii) without restrictions. All cigarettes were smoked ad lib through a smoking topography unit.Background: Despite considerable use of make your own (MYO) cigarettes worldwide and increasing use in the United States relatively little is known about how these cigarettes are smoked and the resultant toxicant exposure.Results: Plasma nicotine significantly increased after cigarettes in all conditions except PMM in the intense smoking paradigm. Puff volume, puff duration, total puff volume, and puff velocity did not differ between cigarette types but the puffs per cigarette and time to smoke were significantly smaller for RYO compared with PMM and FM. Regardless of the cigarette, participants consumed the first three puffs more vigorously than the last three puffs.Conclusions: Despite the belief of many of their consumers, smoking MYO cigarettes is not a safe alternative to FM cigarettes. Like FM, MYO cigarettes expose their users to harmful constituents of tobacco smoke. Despite differences in size and design their puffing profiles are remarkably similar.Impact: These data are relevant to health and regulatory considerations on the MYO cigarettes.
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U2 - 10.1158/1055-9965.EPI-14-0280
DO - 10.1158/1055-9965.EPI-14-0280
M3 - Article
C2 - 24925675
AN - SCOPUS:84907164574
SN - 1055-9965
VL - 23
SP - 1793
EP - 1803
JO - Cancer Epidemiology Biomarkers and Prevention
JF - Cancer Epidemiology Biomarkers and Prevention
IS - 9
ER -