Maintenance therapy in solid tumors

Marie Anne Smit, John L. Marshall

Research output: Contribution to journalReview articlepeer-review


The concept of maintenance therapy has been well studied in hematologic malignancies, and now, an increasing number of clinical trials explore the role of maintenance therapy in solid cancers. Both biological and lower-intensity chemotherapeutic agents are currently being evaluated as maintenance therapy. However, despite the increase in research in this area, there has not been consensus about the definition and timing of maintenance therapy. In this review, we will focus on continuation maintenance therapy and switch maintenance therapy in patients with metastatic solid tumors who have achieved stable disease, partial response, or complete response after first-line treatment.

Original languageEnglish (US)
Pages (from-to)247-258
Number of pages12
JournalCommunity Oncology
Issue number8
StatePublished - Aug 1 2012

ASJC Scopus subject areas

  • Hematology
  • Oncology


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