Abstract
OBJECTIVES: To estimate in a community-dwelling elderly population the magnitude of renal function misclassification, occurring when persons with normal serum creatinine have reduced glomerular filtration rate (GFR), and to describe the participant characteristics related to misclassification. DESIGN: Cross-sectional. SETTING: Population-based study of older Italian people. PARTICIPANTS: Six hundred sixty participants aged 65 to 92 with normal serum creatinine. MEASUREMENTS: GFR was estimated using the Cockcroft-Gault equation and creatinine clearance (CrCl) calculated from 24-hour urine collection. RESULTS: In participants with normal serum creatinine, 39% and 25% had moderate renal function impairment (GFR
Original language | English (US) |
---|---|
Pages (from-to) | 816-823 |
Number of pages | 8 |
Journal | Journal of the American Geriatrics Society |
Volume | 55 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2007 |
Externally published | Yes |
Keywords
- Creatinine
- Elderly
- GFR
- Misclassification bias
ASJC Scopus subject areas
- Geriatrics and Gerontology