MAGNETOFLUIDICS-ENABLED POINT-OF-CARE SARS-COV-2 DIAGNOSTICS

Alexander Y. Trick, Fan En Chen, Liben Chen, Pei Wei Lee, Alexander Hasnain, Heba H. Mostafa, Karen C. Carroll, Tza Huei Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

As the SARS-CoV-2 virus continues to mutate, global eradication of infections is unlikely, and COVID-19 is predicted to become a seasonal or endemic disease like influenza. Widespread detection of variant strains will be critical to inform policy decisions to mitigate further spread, and post-pandemic multiplexed screening of respiratory viruses will be necessary to properly manage patients presenting with similar respiratory symptoms. We have developed a portable, magnetofluidic platform for multiplexed PCR testing in <30 min. Cartridges were designed for multiplexed detection of SARS-CoV-2 with either distinctive variant mutations or with Influenza A and B and tested with clinical samples.

Original languageEnglish (US)
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages739-740
Number of pages2
ISBN (Electronic)9781733419031
StatePublished - 2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: Oct 10 2021Oct 14 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2110/14/21

Keywords

  • Magnetofluidics
  • PCR
  • SARS-CoV-2
  • Sample Preparation

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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