MAGNETOFLUIDIC-ENABLED POINT-OF-CARE DETECTION OF MULTI-DRUG RESISTANT CANDIDA AURIS IN < 30 MINUTES

Pei Wei Lee, Marissa Totten, Kushagra Shah, Fan En Chen, Liben Chen, Alexander Y. Trick, Sean X. Zhang, Kuangwen Hsieh, Tza Huei Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Candida auris infection is an emerging global health issue which requires rapid screening to control the spread. However, the existing diagnosis method requires complex sample preparation steps and costly instruments that limited its utility to centralized laboratories. In response, we present POC.auris, a portable device, which uses magnetofluidics and miniaturized PCR coupled with handheld lysis method that can detect C. auris cells from patient swab or environmental sponge liquids in < 30 min and reaches 100 CFU/mL limit-of-detection.

Original languageEnglish (US)
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages771-772
Number of pages2
ISBN (Electronic)9781733419031
StatePublished - 2021
Externally publishedYes
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: Oct 10 2021Oct 14 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2110/14/21

Keywords

  • Candida auris
  • magnetofluidics
  • point-of-care

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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