Lymphoplasmapheresis in Rheumatoid Arthritis

Stuart A. Rosenberg, Daniel J. Wallace, Dennis Goldfinger, James R. Klinenberg

Research output: Contribution to journalLetterpeer-review


To the Editor: The recent report by Wallace et al. (June 10 issue)1 on the effect of lymphoplasmapheresis in rheumatoid arthritis employed a well-controlled double-blind protocol. Unfortunately, interpretation of the results was at best rather impressionistic. Simply stated, the data showed that there was no significant difference in any assessment index between the sham and real lymphoplasmapheresis groups at the end of nine treatments. In order to make it appear that real differences existed, the data had to be manipulated. For example, there is no significant difference in the Ritchie Index joint scores between the two experimental groups at. . .

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Issue number20
StatePublished - Nov 11 1982

ASJC Scopus subject areas

  • General Medicine


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