Lymphoepithelioma-like carcinoma of the urinary bladder: Report of a rare case

Naorem Gopendro Singh, Abul Ala Syed R. Mannan, Amre A. Rifaat, Mirza Kahvic

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Lymphoepithelioma-like carcinoma (LELC) is a rare malignant neoplasm in the urinary bladder, which can histologically mimic lymphoma, poorly differentiated invasive transitional cell carcinoma or poorly differentiated squamous cell carcinoma with a lymphoplasmacytic background. A urinary bladder tumor was identified in a 65-year-old man suffering from hematuria for several weeks. Transurethral biopsy revealed an undifferentiated tumor with prominent lymphocytes and plasma cell infiltration. Immunohistochemical evaluation showed positive staining for cytokeratin and epithelial membrane antigen. Subsequent radical cystectomy showed pure LELC. We present the case to highlight the significance of recognizing this unusual bladder tumor and discuss the important differential diagnosis, treatment options and prognosis.

Original languageEnglish (US)
Pages (from-to)478-481
Number of pages4
JournalAnnals of Saudi medicine
Issue number6
StatePublished - Nov 2009
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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