Lymphatic spread of pagetic osteogenic sarcoma detected by bone scan

Alexandre Arkader, Carol D. Morris

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([99mTc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating hematogenous spread. A bone scan win often fail to demonstrate lymph nodes metastases until there is mineralization at the affected node. In this report, we highlight an interesting case of a patient with secondary osteogenic sarcoma (OS) from Paget's disease in the distal femur with non-ossified inguinal nodal metastasis diagnosed with [99mTc]MDP. Lymph node involvement was not appreciated on plain radiographs or computed tomography (CT).

Original languageEnglish (US)
Pages (from-to)131-134
Number of pages4
JournalCancer Imaging
Issue number1
StatePublished - 2008
Externally publishedYes


  • Bone scan
  • Lymph node metastasis
  • Metastatic sarcoma
  • Paget's sarcoma

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Oncology
  • Radiology Nuclear Medicine and imaging


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