TY - JOUR
T1 - Lower respiratory infections among hospitalized children in New Caledonia
T2 - A pilot study for the pneumonia etiology research for child health project
AU - Mermond, Sylvain
AU - Zurawski, Virginie
AU - D'Ortenzio, Eric
AU - Driscoll, Amanda J.
AU - Deluca, Andrea N.
AU - Deloria-Knoll, Maria
AU - Moïsi, Jennifer C.
AU - Murdoch, David R.
AU - Missotte, Isabelle
AU - Besson-Leaud, Laurent
AU - Chevalier, Cyril
AU - Debarnot, Vincent
AU - Feray, Fabien
AU - Noireterre, Stephanie
AU - Duparc, Bernard
AU - Fresnais, Frederique
AU - O'Connor, Olivia
AU - Dupont-Rouzeyrol, Myrielle
AU - Levine, Orin S.
N1 - Funding Information:
Supplement sponsorship. This article was published as part of a supplement entitled ‘‘Pneumonia Etiology Research for Child Health,’’ sponsored by a grant from The Bill & Melinda Gates Foundation to the PERCH Project of Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Potential conflicts of interest. All authors: No reported conflicts.
PY - 2012/4/1
Y1 - 2012/4/1
N2 - We conducted a prospective pilot study over a 1-year period in New Caledonia in preparation for the Pneumonia Research for Child Health (PERCH) project. The pathogens associated with hospitalized lower respiratory infections in children were identified through the use of culture of induced sputum and blood, urinary antigen detection, polymerase chain reaction (PCR) on respiratory specimens, and serology on paired sera. Respiratory viruses were detected on respiratory specimens by immunofluorescence and PCR, and by serology on paired sera. Pathogens were detected in 87.9% of the 108 hospitalized cases. Viruses represented 81.6% of the 152 pathogens detected. Respiratory syncytial virus and rhinovirus were the most frequent, accounting for 32.2% and 24.3% of the pathogens identified, respectively. Only 26.3% of 99 induced sputum specimens collected were determined to be of good quality, which may be a consequence of the collection method used.
AB - We conducted a prospective pilot study over a 1-year period in New Caledonia in preparation for the Pneumonia Research for Child Health (PERCH) project. The pathogens associated with hospitalized lower respiratory infections in children were identified through the use of culture of induced sputum and blood, urinary antigen detection, polymerase chain reaction (PCR) on respiratory specimens, and serology on paired sera. Respiratory viruses were detected on respiratory specimens by immunofluorescence and PCR, and by serology on paired sera. Pathogens were detected in 87.9% of the 108 hospitalized cases. Viruses represented 81.6% of the 152 pathogens detected. Respiratory syncytial virus and rhinovirus were the most frequent, accounting for 32.2% and 24.3% of the pathogens identified, respectively. Only 26.3% of 99 induced sputum specimens collected were determined to be of good quality, which may be a consequence of the collection method used.
UR - http://www.scopus.com/inward/record.url?scp=84858120818&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858120818&partnerID=8YFLogxK
U2 - 10.1093/cid/cir1070
DO - 10.1093/cid/cir1070
M3 - Article
C2 - 22403234
AN - SCOPUS:84858120818
SN - 1058-4838
VL - 54
SP - S180-S189
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - SUPPL. 2
ER -