Lots of Movement in Gut and Parkinson's Research

Gabriela Mercado, Patrik Brundin

Research output: Contribution to journalShort surveypeer-review

Abstract

A new mouse model of Parkinson's disease (PD) demonstrates α-synuclein pathology spreading from the gut to the brain via the vagus nerve (Kim et al., Neuron, 2019). The pathology is associated with motor and non-motor behavioral deficits in wild-type mice. These findings support the idea that the gut could be a starting point for PD.

Original languageEnglish (US)
Pages (from-to)687-689
Number of pages3
JournalTrends in Endocrinology and Metabolism
Volume30
Issue number10
DOIs
StatePublished - Oct 2019
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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