Longitudinal Trends in Sexual Behaviors with Advancing Age and Menopause Among Women With and Without HIV-1 Infection

Tonya N. Taylor, Jeremy Weedon, Elizabeth T. Golub, Stephen E. Karpiak, Monica Gandhi, Mardge H. Cohen, Alexandra M. Levine, Howard L. Minkoff, Adebola A. Adedimeji, Lakshmi Goparaju, Susan Holman, Tracey E. Wilson

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


We assessed changes in self-reported sexual activity (SA) over 13 years among HIV-infected and uninfected women. The impact of aging and menopause on SA and unprotected anal or vaginal intercourse (UAVI) was examined among women in the Women’s Interagency HIV Study (WIHS), stratifying by HIV status and detectable viral load among HIV-infected women. Generalized mixed linear models were fitted for each outcome, adjusted for relevant covariates. HIV-uninfected women evidenced higher levels of SA and UAVI than HIV-infected. The odds of SA declined by 62–64 % per decade of age. The odds of SA in a 6-month interval for women aged 40–57 declined by 18–22 % post-menopause (controlling for age). Among HIV+/detectable women only, the odds of any UAVI decreased by 17 % per decade of age; the odds of UAVI were unchanged pre-menopause, and then decreased by 28 % post-menopause. Elucidating the factors accounting for ongoing unprotected sex among older women should inform interventions.

Original languageEnglish (US)
Pages (from-to)931-940
Number of pages10
JournalAIDS and behavior
Issue number5
StatePublished - May 1 2015


  • Aging
  • Menopause
  • Sexual activity
  • Sexual risk behaviors
  • Women’s Interagency HIV Study (WIHS)

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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