Long-term retention of implicit learning in Huntington's disease

Frederick W. Bylsma, George W. Rebok, Jason Brandt

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Implicit learning was examined in 15 Huntington's disease (HD) patients and 15 control subjects (NC) using a semantic decision-making task. HD patients demonstrated only slightly reduced priming; like NC subjects, their decision times decreased over repeated presentations, though to a somewhat lesser degree. On explicit recognition testing, the HD group made significantly more false positive errors than did the control group, suggesting an impairment of effortful retrieval. The groups displayed equivalent retention of implicitly learned material after 6 months. The striatal neuronal loss of early Huntington's disease does not markedly affect priming or retention of primed stimuli, but may alter explicit memory judgements.

Original languageEnglish (US)
Pages (from-to)1213-1221
Number of pages9
Issue number12
StatePublished - Dec 1991

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience


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