Long-term course of hospitalization for schizophrenia: Part II. Change with passage of time

William W. Eaton, Warren Bilker, Josep M. Haro, Helen Herrman, Preben Bo Mortensen, Hugh Freeman, Philip Burgess

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

This analysis examines the notion of progressive deterioration in schizophrenia, using long-term followup data on hospital episodes in defined cohorts from psychiatric case registers in Victoria, Australia; Denmark; and Salford, England. The analyses differentiate heterogeneity existing at the first hospitalization for schizophrenia, which produces a widely varying natural course, from heterogeneity that develops over time, as episodes of hospitalization occur. Episodes of hospitalization for schizophrenia tend to cluster earlier rather than later in the treatment career, suggesting a progressive amelioration rather than deterioration. When overall chronicity is adjusted, each additional episode of hospitalization lowers the risk for a further hospitalization by about 10 percent.

Original languageEnglish (US)
Pages (from-to)229-241
Number of pages13
JournalSchizophrenia bulletin
Volume18
Issue number2
DOIs
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health

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