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Liver regeneration after living adult right lobe transplantation

  • I. R. Kamel
  • , N. Erbay
  • , G. Warmbrand
  • , J. B. Kruskal
  • , E. A. Pomfret
  • , V. Raptopoulos

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The purpose of this study was to describe liver regeneration in patients undergoing living-adult liver transplantation. Methods: This prospective study included 10 donors and eight recipients who had a total of 65 computed tomographic (CT) scans. All patients had preoperative CT (n = 18), and follow-up CT scans (n = 47) were obtained for up to 14 months after transplantation. Liver and spleen volumes were measured by hand tracing each organ on the axial portal venous phase images. Results: Both donors and recipients showed immediate increases in liver volume. However, liver regeneration was significantly faster and reached a higher peak in recipients than in donors. Splenic volume in donors demonstrated an initial increase followed by a decline, reaching the preoperative volume after 1 year. Splenic volume in recipients demonstrated immediate decline postoperatively. Conclusion: Restoration of liver volume occurred rapidly after transplantation, but followed different patterns in donors and recipients. Deviation from these patterns warrants further investigation.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalAbdominal Imaging
Volume28
Issue number1
DOIs
StatePublished - Jan 2003

Keywords

  • Blood supply
  • Computed tomography
  • Image processing
  • Liver transplantation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

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