TY - JOUR
T1 - Lissamine Green Staining in the Clinical Diagnosis of Xerophthalmia
AU - Emran, Nani
AU - Sommer, Alfred
PY - 1979/12
Y1 - 1979/12
N2 - Lissamine green staining of the conjunctiva, a new and widely heralded aid for diagnosing early xerophthalmia, was found to be a reasonably specific but inadequately sensitive test for practical use. While 82% of clinically normal children failed to show staining, so did 57% with night blindness, 29% with vitamin A responsive Bitot's spots, and, most significantly, 26% with severe, vitamin A related corneal involvement. The test also failed to distinguish vitamin A responsive “Bitot's spots” from nonresponsive ones.
AB - Lissamine green staining of the conjunctiva, a new and widely heralded aid for diagnosing early xerophthalmia, was found to be a reasonably specific but inadequately sensitive test for practical use. While 82% of clinically normal children failed to show staining, so did 57% with night blindness, 29% with vitamin A responsive Bitot's spots, and, most significantly, 26% with severe, vitamin A related corneal involvement. The test also failed to distinguish vitamin A responsive “Bitot's spots” from nonresponsive ones.
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U2 - 10.1001/archopht.1979.01020020549009
DO - 10.1001/archopht.1979.01020020549009
M3 - Article
C2 - 316322
AN - SCOPUS:0018640505
SN - 2168-6165
VL - 97
SP - 2333
EP - 2335
JO - JAMA Ophthalmology
JF - JAMA Ophthalmology
IS - 12
ER -