Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates

Christopher E. Von Seggern; Susanne C. Moyer; Robert J. Cotter

doi:10.1021/ac0262006

Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates

Christopher E. Von Seggern, Susanne C. Moyer, Robert J. Cotter

School of Medicine

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

A 2.94-μm Er:YAG laser for IR atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used for the analysis of sialylated oligosaccharides. This approach provided the opportunity to utilize liquid matrixes and is effective in determining structural features - sequence, branching, and linkage - of intact, fully sialylated molecular species.

Original language	English (US)
Pages (from-to)	3212-3218
Number of pages	7
Journal	Analytical Chemistry
Volume	75
Issue number	13
DOIs	https://doi.org/10.1021/ac0262006
State	Published - Jul 1 2003

ASJC Scopus subject areas

Analytical Chemistry

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10.1021/ac0262006

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title = "Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates",

abstract = "A 2.94-μm Er:YAG laser for IR atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used for the analysis of sialylated oligosaccharides. This approach provided the opportunity to utilize liquid matrixes and is effective in determining structural features - sequence, branching, and linkage - of intact, fully sialylated molecular species.",

author = "{Von Seggern}, {Christopher E.} and Moyer, {Susanne C.} and Cotter, {Robert J.}",

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AU - Moyer, Susanne C.

AU - Cotter, Robert J.

PY - 2003/7/1

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N2 - A 2.94-μm Er:YAG laser for IR atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used for the analysis of sialylated oligosaccharides. This approach provided the opportunity to utilize liquid matrixes and is effective in determining structural features - sequence, branching, and linkage - of intact, fully sialylated molecular species.

AB - A 2.94-μm Er:YAG laser for IR atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used for the analysis of sialylated oligosaccharides. This approach provided the opportunity to utilize liquid matrixes and is effective in determining structural features - sequence, branching, and linkage - of intact, fully sialylated molecular species.

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Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates

Abstract

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