Lipid Signaling

B. Tu-Sekine, D. M. Raben

Research output: Chapter in Book/Report/Conference proceedingChapter


A special group of cellular lipids, known as lipid messengers or bioactive lipids participates in signaling cascades in all organisms, from bacteria to mammals. Bioactive lipids are potent signaling molecules; their appearance is tightly controlled both in space and time. The regulated production of lipid second messengers is critical for the coordinated functioning of a cell, and various systems such as feedback regulation and signal convergence from multiple pathways help to ensure that disruption of a single lipid metabolizing enzyme does not compromise the intricate communications network.

Original languageEnglish (US)
Title of host publicationMolecular Cell Biology
PublisherElsevier Inc.
Number of pages7
ISBN (Electronic)9780123944474
ISBN (Print)9780123947963
StatePublished - Jan 1 2016


  • Arachidonic acid
  • Bioactive lipid
  • Ceramide
  • Diacylglycerol
  • Eicosanoid
  • Endocannabinoid
  • Glycerolipid
  • Glycerophospholipid
  • Lipid metabolism
  • Lipid signaling
  • Lipid-binding domain
  • Lysophospholipid
  • Phosphatidic acid
  • Phosphatidylinositol
  • Phosphoinositide
  • Second messenger
  • Sphingolipid

ASJC Scopus subject areas

  • Medicine(all)


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