Lipid Signaling

B. Tu-Sekine; D. M. Raben

doi:10.1016/B978-0-12-394447-4.10023-9

Lipid Signaling

B. Tu-Sekine, D. M. Raben

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

A special group of cellular lipids, known as lipid messengers or bioactive lipids participates in signaling cascades in all organisms, from bacteria to mammals. Bioactive lipids are potent signaling molecules; their appearance is tightly controlled both in space and time. The regulated production of lipid second messengers is critical for the coordinated functioning of a cell, and various systems such as feedback regulation and signal convergence from multiple pathways help to ensure that disruption of a single lipid metabolizing enzyme does not compromise the intricate communications network.

Original language	English (US)
Title of host publication	Molecular Cell Biology
Publisher	Elsevier Inc.
Pages	194-200
Number of pages	7
Volume	1
ISBN (Electronic)	9780123944474
ISBN (Print)	9780123947963
DOIs	https://doi.org/10.1016/B978-0-12-394447-4.10023-9
State	Published - Jan 1 2016

Keywords

Arachidonic acid
Bioactive lipid
Ceramide
Diacylglycerol
Eicosanoid
Endocannabinoid
Glycerolipid
Glycerophospholipid
Lipid metabolism
Lipid signaling
Lipid-binding domain
Lysophospholipid
Phosphatidic acid
Phosphatidylinositol
Phosphoinositide
Second messenger
Sphingolipid

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-12-394447-4.10023-9

Cite this

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title = "Lipid Signaling",

abstract = "A special group of cellular lipids, known as lipid messengers or bioactive lipids participates in signaling cascades in all organisms, from bacteria to mammals. Bioactive lipids are potent signaling molecules; their appearance is tightly controlled both in space and time. The regulated production of lipid second messengers is critical for the coordinated functioning of a cell, and various systems such as feedback regulation and signal convergence from multiple pathways help to ensure that disruption of a single lipid metabolizing enzyme does not compromise the intricate communications network.",

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AU - Raben, D. M.

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AB - A special group of cellular lipids, known as lipid messengers or bioactive lipids participates in signaling cascades in all organisms, from bacteria to mammals. Bioactive lipids are potent signaling molecules; their appearance is tightly controlled both in space and time. The regulated production of lipid second messengers is critical for the coordinated functioning of a cell, and various systems such as feedback regulation and signal convergence from multiple pathways help to ensure that disruption of a single lipid metabolizing enzyme does not compromise the intricate communications network.

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KW - Bioactive lipid

KW - Ceramide

KW - Diacylglycerol

KW - Eicosanoid

KW - Endocannabinoid

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KW - Glycerophospholipid

KW - Lipid metabolism

KW - Lipid signaling

KW - Lipid-binding domain

KW - Lysophospholipid

KW - Phosphatidic acid

KW - Phosphatidylinositol

KW - Phosphoinositide

KW - Second messenger

KW - Sphingolipid

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ER -

Lipid Signaling

Abstract

Keywords

ASJC Scopus subject areas

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