Life course socioeconomic position and subcl inical disease: The jackson heart study

Bradley Deere, Michael Griswold, Seth Lirette, Ervin Fox, Mario Sims

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Objectives: African Americans experience higher rates of cardiovascular disease (CVD) and lower childhood and adult socioeconomic position (SEP). Research that examines the associations of multiple measures of SEP with subclinical CVD markers among African Americans is limited. Methods: Data from the Jackson Heart Study (JHS) were used to examine crosssectional associations of childhood SEP and adult SEP with subclinical markers among 4,756 African American participants (mean age 54, 64% female), adjusting for age, health behaviors and CVD risk factors. Subclinical markers included prevalent left ventricular hypertrophy (LVH), peripheral artery disease (PAD), coronary artery calcification (CAC), and carotid intima-media thickness (CIMT). Results: The prevalence of LVH, PAD and CAC was 7%, 6% and 45%, respectively. The mean CIMT was .72 ± .17 mm. In fully-adjusted models, having a college education was inversely associated with PAD (OR, .27; 95% CI .13,.56) and CIMT (?=-29.7, P<.01). Income was inversely associated with LVH after adjustment for health behaviors (OR, .49 95% CI .25,.96), though associations attenuated in the fully-adjusted model. Measures of childhood SEP (material resources and mother's education) were not consistently associated with subclinical disease measures other than a positive association between material resources and CIMT. Conclusions: Subclinical disease markers were patterned by adult SEP measures among African Americans.

Original languageEnglish (US)
Pages (from-to)355-362
Number of pages8
JournalEthnicity and Disease
Issue number3
StatePublished - Jun 1 2016
Externally publishedYes


  • African American
  • Socioeconomic Position
  • Subclinical Cardiovascular Disease

ASJC Scopus subject areas

  • Epidemiology


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