Abstract
Objective: To describe a case of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated encephalitis. Methods: The clinical and ancillary data and brain MRIs were gathered retrospectively by chart review. Relevant literature on similar cases was also reviewed. Results: The diagnosis of LGI1 antibody-associated autoimmune encephalitis was based on the typical clinical presentation of seizures, psychiatric symptoms, and memory loss as well as negative diagnostic testing for cancer; the diagnosis was confirmed by positive LGI1 antibody. The patient responded favorably to treatment with IV immunoglobulin and continues to do well. Conclusion: LGI1 antibody-associated encephalitis has increasingly been recognized as a primary autoimmune disorder with good prognosis and response to treatment.
| Original language | English (US) |
|---|---|
| Article number | e51 |
| Journal | Neurology: Neuroimmunology and NeuroInflammation |
| Volume | 1 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2014 |
| Externally published | Yes |
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
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