TY - JOUR
T1 - Leptin and reproduction
AU - Bi, Sheng
AU - Gavrilova, Oksana
AU - Gong, Da Wei
AU - Marcus-Samuels, Bernice
AU - Mason, Mark M.
AU - Reitman, Marc L.
N1 - Funding Information:
Supported by Research Grant (HD28964, to DWB) from the National Institute of Child Health and Human Development, NIH, US Public Health Service.
PY - 1999/6
Y1 - 1999/6
N2 - Leptin is a hormone that regulates metabolic efficiency, energy expenditure, and food intake (1). Leptin is secreted by adipose tissue in proportion to its degree of adiposity, and thus indicates the level of body fat stores. A low leptin level, signifying a paucity of fat, serves as a warning of food scarcity and causes animals to conserve fuel. High leptin levels, indicating excess fuel stores, signal that adipose stores are sufficient for energy-demanding activities. Many of the actions of leptin are thought to occur due to its effects on hypothalamic neurons. In this review we will analyze how these hypotheses apply to reproduction.
AB - Leptin is a hormone that regulates metabolic efficiency, energy expenditure, and food intake (1). Leptin is secreted by adipose tissue in proportion to its degree of adiposity, and thus indicates the level of body fat stores. A low leptin level, signifying a paucity of fat, serves as a warning of food scarcity and causes animals to conserve fuel. High leptin levels, indicating excess fuel stores, signal that adipose stores are sufficient for energy-demanding activities. Many of the actions of leptin are thought to occur due to its effects on hypothalamic neurons. In this review we will analyze how these hypotheses apply to reproduction.
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M3 - Article
AN - SCOPUS:0032872354
SN - 1081-1672
VL - 22
SP - 236
EP - 238
JO - Journal of Clinical Ligand Assay
JF - Journal of Clinical Ligand Assay
IS - 2
ER -