Latent reservoirs for HIV-1

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Combination therapy for HIV-1 infection can reduce viremia to undetectable levels, suggesting that prolonged treatment might eradicate the infection. However, one potential mechanism for viral persistence involves the establishment of a state of latent infection. Recent studies have directly confirmed that HIV-1 establishes a state of latent infection in resting memory CD4+ T cells in vivo. This reservoir is likely to frustrate current efforts to eradicate the infection with combination therapy.

Original languageEnglish (US)
Pages (from-to)5-11
Number of pages7
JournalCurrent opinion in infectious diseases
Issue number1
StatePublished - Feb 1999

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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