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Late meningitis and a nonabsorbable stent in recurrent Rathke’s cleft cyst: illustrative case

  • Simona Serioli
  • , Vincenzo Mastropasqua
  • , Giorgia De Rosa
  • , Romina Ebrahimian
  • , Pierpaolo Mattogno
  • , Mario Rigante
  • , Simona Gaudino
  • , Salvatore Maria Corsello
  • , Liverana Lauretti
  • , Rita Murri
  • , Marco Gessi
  • , Alessandro Olivi
  • , Francesco Doglietto

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND The management of recurrent Rathke’s cleft cysts (RCCs) remains challenging. The off-label application of steroid-eluting bioabsorbable or nonabsorbable intracystic stents has been recently described. Early outcomes and complications of this treatment have been described as well, but long-term data are lacking. OBSERVATIONS A 31-year-old woman who had undergone 3 prior transsphenoidal surgeries for recurrent RCC at other institutions was admitted for methi cilli n-sus cepti ble Staphylococcus aureus meningitis. Five years earlier, a nonabsorbable stent had been placed in the cyst using a microsurgical transsphenoidal approach. RCC recurrence had been radiologically evident after 2 years but was clinically asymptomatic. Acute cerebrospinal fluid leakage and other causes of meningitis were ruled out; the stent was occluded. After antibiotic therapy and resolution of the meningitis, the patient underwent endoscopic removal of the catheter, excision of the cyst, and reconstruction with a nasoseptal flap. At the 18-month follow-up, she remained neurologically intact, under replacement therapy, and with no signs of recurrence. LESSONS The authors report the first case of late meningitis due to a nonabsorbable stent positioned for the treatment of a recurrent RCC. Currently, data on the long-term outcomes, failure rates, and complications of stents for RCC are limited.

Original languageEnglish (US)
Article numberCASE2477
JournalJournal of Neurosurgery: Case Lessons
Volume8
Issue number13
DOIs
StatePublished - Sep 1 2024
Externally publishedYes

Keywords

  • Case report
  • Intracystic stent
  • Meningitis
  • Nonabsorbable device
  • Recurrent Rathke’s cleft cyst

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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