Large tumefactive igg4-related disease: Histologic, cytologic, and immunohistochemical features of a very unusual case

Israh Akhtar; Veena Shenoy; Majid Khan; Ali G. Saad

doi:10.1097/PAI.0000000000000571

Large tumefactive igg4-related disease: Histologic, cytologic, and immunohistochemical features of a very unusual case

Israh Akhtar, Veena Shenoy, Majid Khan, Ali G. Saad

Research output: Contribution to journal › Article › peer-review

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a regional or systemic multiorgan lymphoplasmacytic inflammatory disease of unknown etiology. It has been described in numerous organs and anatomic locations. Review of the literature shows that when the disease involves the retroperitoneum it causes retroperitoneal fibrosis. Tumefactive IgG4-RD of the retroperitoneum has not been previously reported. In this report, we describe the first case of a large retroperitoneal tumefactive IgG4-RD along with its histologic, cytologic, and immunohistochemical characteristics.

Original language	English (US)
Pages (from-to)	E21-E25
Journal	Applied Immunohistochemistry and Molecular Morphology
Volume	28
Issue number	3
DOIs	https://doi.org/10.1097/PAI.0000000000000571
State	Published - Mar 1 2020
Externally published	Yes

Keywords

IgG4-related disease
Retroperitoneal mass
Soft tissue tumor

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Medical Laboratory Technology

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10.1097/PAI.0000000000000571

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abstract = "Immunoglobulin G4-related disease (IgG4-RD) is a regional or systemic multiorgan lymphoplasmacytic inflammatory disease of unknown etiology. It has been described in numerous organs and anatomic locations. Review of the literature shows that when the disease involves the retroperitoneum it causes retroperitoneal fibrosis. Tumefactive IgG4-RD of the retroperitoneum has not been previously reported. In this report, we describe the first case of a large retroperitoneal tumefactive IgG4-RD along with its histologic, cytologic, and immunohistochemical characteristics.",

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AU - Akhtar, Israh

AU - Shenoy, Veena

AU - Khan, Majid

AU - Saad, Ali G.

PY - 2020/3/1

Y1 - 2020/3/1

N2 - Immunoglobulin G4-related disease (IgG4-RD) is a regional or systemic multiorgan lymphoplasmacytic inflammatory disease of unknown etiology. It has been described in numerous organs and anatomic locations. Review of the literature shows that when the disease involves the retroperitoneum it causes retroperitoneal fibrosis. Tumefactive IgG4-RD of the retroperitoneum has not been previously reported. In this report, we describe the first case of a large retroperitoneal tumefactive IgG4-RD along with its histologic, cytologic, and immunohistochemical characteristics.

AB - Immunoglobulin G4-related disease (IgG4-RD) is a regional or systemic multiorgan lymphoplasmacytic inflammatory disease of unknown etiology. It has been described in numerous organs and anatomic locations. Review of the literature shows that when the disease involves the retroperitoneum it causes retroperitoneal fibrosis. Tumefactive IgG4-RD of the retroperitoneum has not been previously reported. In this report, we describe the first case of a large retroperitoneal tumefactive IgG4-RD along with its histologic, cytologic, and immunohistochemical characteristics.

KW - IgG4-related disease

KW - Retroperitoneal mass

KW - Soft tissue tumor

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Large tumefactive igg4-related disease: Histologic, cytologic, and immunohistochemical features of a very unusual case

Abstract

Keywords

ASJC Scopus subject areas

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