Abstract
Large cell neuroendocrine carcinoma (LCNEC) is part of the neuroendocrine spectrum of pulmonary tumors. This increasingly recognized tumor has been reported to have 5-year actuarial survival rates following resection that are worse than those described for other variants of non-small cell lung cancer (NSCLC). Therefore, debate has emerged regarding whether the tumors should be classified and treated as NSCLC or small-cell lung cancer. This article reviews the tumor characterization, biology, presentation and diagnosis, surgical therapy, results of therapy, and long term prognosis of patients with LCNEC.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 206-210 |
| Number of pages | 5 |
| Journal | Seminars in thoracic and cardiovascular surgery |
| Volume | 18 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2006 |
| Externally published | Yes |
Keywords
- large cell neuroendocrine carcinoma
- neuroendocrine spectrum
- non-small cell lung cancer
- pulmonary tumors
ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine