Landau-Kleffner syndrome responsive to levetiracetam

Eric H. Kossoff, Dana Boatman, John M. Freeman

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


A 5-year-old girl with Landau-Kleffner syndrome is discussed. The child began having seizures at age 4 associated with language deterioration despite anticonvulsant therapy. With levetiracetam monotherapy to a dose of 60mg/kg/day and discontinuation of carbamazepine and valproic acid, her language has improved and seizures are controlled. Levetiracetam should be considered as therapy for Landau-Kleffner syndrome.

Original languageEnglish (US)
Pages (from-to)571-575
Number of pages5
JournalEpilepsy and Behavior
Issue number5
StatePublished - Oct 2003


  • Acquired epileptic aphasia
  • Epilepsy
  • Landau-Kleffner syndrome
  • Levetiracetam

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience


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