@inproceedings{299c2c069918425fa69d915bd8aa0299,
title = "Labeling of cells with silver and gold host-guest nanocomposites",
abstract = "Nanocomposites combine the properties of nano-sized inorganic guest atoms/molecules with their nanoscopic size polymer host. Using poly(amidoamine) (PAMAM) dendrimers as templates we have synthesized water-soluble, biocompatible, fluorescent, and stable nanocomposites with regulated surface charge and controlled size for cell labeling studies. Silver \{Ag 0-PAMAM\} and gold \{Au0PAMAM\} dendrimer nanocomposites were used for in vitro cell labeling. The results indicate that surface charge plays a significant role in biocompatibility and cellular intemalization. Cytotoxicity (or lack thereof) of the host dendrimers and related nanocomposites was evaluated in normal and cancer cells using XTT assay. Cellular uptake of nanoparticles was examined by TEM and confocal microscopy. We demonstrate that nanocomposites can be used as cell biomarkers.",
keywords = "Cell labeling, Poly(amidoamine) dendrimer, Silver and gold/dendrimer nanocomposite",
author = "Balogh, \{Lajos P.\} and Wojciech Lesniak and Sinani, \{Vladimir A.\} and Bielinska, \{Anna U.\} and Kai Sun and Nair, \{Bindu M.\} and Emily Waite and Kariapper, \{Muhammed S.T.\} and Khan, \{Mohamed K.\}",
year = "2006",
language = "English (US)",
isbn = "0976798573",
series = "2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings",
pages = "462--465",
booktitle = "2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings",
note = "2006 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2006 Technical Proceedings ; Conference date: 07-05-2006 Through 11-05-2006",
}