Krüppel-like factors in the vascular endothelium

Guillermo García-Cardeña, Guadalupe Villarreal

Research output: Chapter in Book/Report/Conference proceedingChapter


Although Krüppel-like factors (KLFs) have been the subject of extensive biological investigation, the role of this family of transcription factors in the biology and pathophysiology of the vascular endothelium is just becoming apparent. Most investigative efforts thus far have focused on KLF2, its contribution to the endothelial vasoprotective phenotype, and its possible impact on atherogenesis. This chapter reflects on the current state of the field and highlights evolving areas where KLFs are emerging as important regulators of endothelial function.

Original languageEnglish (US)
Title of host publicationThe Biology of Krüppel-like Factors
PublisherSpringer Japan
Number of pages12
ISBN (Print)9784431877745
StatePublished - 2009

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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