KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations

Pim B. Olthof; Stefan Buettner; Nikolaos Andreatos; Jane Wang; Inger Marie Løes; Doris Wagner; Kazunari Sasaki; Andrea MacHer-Beer; Carsten Kamphues; Ioannis Pozios; Hendrik Seeliger; Daisuke Morioka; Katsunori Imai; Klaus Kaczirek; Timothy M. Pawlik; George Poultsides; Richard Burkhart; Itaru Endo; Hideo Baba; Peter Kornprat; Federico N. Aucejo; Per Eystein Lønning; Katharina Beyer; Matthew J Weiss; Christopher L. Wolfgang; Martin E. Kreis; Georgios A. Margonis

doi:10.1093/bjs/znac147

KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations

Pim B. Olthof, Stefan Buettner, Nikolaos Andreatos, Jane Wang, Inger Marie Løes, Doris Wagner, Kazunari Sasaki, Andrea MacHer-Beer, Carsten Kamphues, Ioannis Pozios, Hendrik Seeliger, Daisuke Morioka, Katsunori Imai, Klaus Kaczirek, Timothy M. Pawlik, George Poultsides, Richard Burkhart, Itaru Endo, Hideo Baba, Peter KornpratFederico N. Aucejo, Per Eystein Lønning, Katharina Beyer, Matthew J Weiss, Christopher L. Wolfgang, Martin E. Kreis, Georgios A. Margonis

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	804-807
Number of pages	4
Journal	British Journal of Surgery
Volume	109
Issue number	9
DOIs	https://doi.org/10.1093/bjs/znac147
State	Published - Sep 1 2022
Externally published	Yes

ASJC Scopus subject areas

Surgery

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Olthof, P. B., Buettner, S., Andreatos, N., Wang, J., Løes, I. M., Wagner, D., Sasaki, K., MacHer-Beer, A., Kamphues, C., Pozios, I., Seeliger, H., Morioka, D., Imai, K., Kaczirek, K., Pawlik, T. M., Poultsides, G., Burkhart, R., Endo, I., Baba, H., ... Margonis, G. A. (2022). KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations. British Journal of Surgery, 109(9), 804-807. https://doi.org/10.1093/bjs/znac147

Olthof, PB, Buettner, S, Andreatos, N, Wang, J, Løes, IM, Wagner, D, Sasaki, K, MacHer-Beer, A, Kamphues, C, Pozios, I, Seeliger, H, Morioka, D, Imai, K, Kaczirek, K, Pawlik, TM, Poultsides, G, Burkhart, R, Endo, I, Baba, H, Kornprat, P, Aucejo, FN, Lønning, PE, Beyer, K, Weiss, MJ, Wolfgang, CL, Kreis, ME & Margonis, GA 2022, 'KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations', British Journal of Surgery, vol. 109, no. 9, pp. 804-807. https://doi.org/10.1093/bjs/znac147

@article{b10b58dcf1ce4bde8705c319c889c4bc,

title = "KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations",

author = "Olthof, {Pim B.} and Stefan Buettner and Nikolaos Andreatos and Jane Wang and L{\o}es, {Inger Marie} and Doris Wagner and Kazunari Sasaki and Andrea MacHer-Beer and Carsten Kamphues and Ioannis Pozios and Hendrik Seeliger and Daisuke Morioka and Katsunori Imai and Klaus Kaczirek and Pawlik, {Timothy M.} and George Poultsides and Richard Burkhart and Itaru Endo and Hideo Baba and Peter Kornprat and Aucejo, {Federico N.} and L{\o}nning, {Per Eystein} and Katharina Beyer and Weiss, {Matthew J} and Wolfgang, {Christopher L.} and Kreis, {Martin E.} and Margonis, {Georgios A.}",

note = "Funding Information: Disclosure. Dr I.M.L. reported receiving 2 personal fees from Bayer, Roche, and Servier outside the submitted work. Dr I.B. reported receiving grants from Taiho Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd, and MSD Pharmaceuticals; and receiving personal fees from Taiho Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd, Takeda Pharmaceutical Co Ltd, Chugai Pharmaceutical Co Ltd, and Eli Lilly Japan outside the submitted work. Dr C.L.W. reported receiving personal fees from Healthcore outside the submitted work. The authors declare no other conflict of interest. Funding Information: G.A.M is supported by the National Institutes of Health/National Cancer Institute Cancer Center Support Grant P30 CA008748. The funding sources had no role in study design, implementation, analysis, or reporting. Acknowledgements ",

year = "2022",

month = sep,

day = "1",

doi = "10.1093/bjs/znac147",

language = "English (US)",

volume = "109",

pages = "804--807",

journal = "British Journal of Surgery",

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TY - JOUR

T1 - KRAS alterations in colorectal liver metastases

T2 - shifting to exon, codon, and point mutations

AU - Olthof, Pim B.

AU - Buettner, Stefan

AU - Andreatos, Nikolaos

AU - Wang, Jane

AU - Løes, Inger Marie

AU - Wagner, Doris

AU - Sasaki, Kazunari

AU - MacHer-Beer, Andrea

AU - Kamphues, Carsten

AU - Pozios, Ioannis

AU - Seeliger, Hendrik

AU - Morioka, Daisuke

AU - Imai, Katsunori

AU - Kaczirek, Klaus

AU - Pawlik, Timothy M.

AU - Poultsides, George

AU - Burkhart, Richard

AU - Endo, Itaru

AU - Baba, Hideo

AU - Kornprat, Peter

AU - Aucejo, Federico N.

AU - Lønning, Per Eystein

AU - Beyer, Katharina

AU - Weiss, Matthew J

AU - Wolfgang, Christopher L.

AU - Kreis, Martin E.

AU - Margonis, Georgios A.

N1 - Funding Information: Disclosure. Dr I.M.L. reported receiving 2 personal fees from Bayer, Roche, and Servier outside the submitted work. Dr I.B. reported receiving grants from Taiho Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd, and MSD Pharmaceuticals; and receiving personal fees from Taiho Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd, Takeda Pharmaceutical Co Ltd, Chugai Pharmaceutical Co Ltd, and Eli Lilly Japan outside the submitted work. Dr C.L.W. reported receiving personal fees from Healthcore outside the submitted work. The authors declare no other conflict of interest. Funding Information: G.A.M is supported by the National Institutes of Health/National Cancer Institute Cancer Center Support Grant P30 CA008748. The funding sources had no role in study design, implementation, analysis, or reporting. Acknowledgements

PY - 2022/9/1

Y1 - 2022/9/1

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JO - British Journal of Surgery

JF - British Journal of Surgery

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ER -

KRAS alterations in colorectal liver metastases: shifting to exon, codon, and point mutations

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