@article{ada26975b0ec4c9e8702ea3b3cafa7db,
title = "Ketogenic Dietary Therapy Controversies for Its Second Century",
abstract = "As the ketogenic diet approaches 100 years of continuous use, we reflect on its successes and consider new avenues of research for the next century. One controversial question is regarding whether ketogenic dietary therapies could be successful first-line treatments for epilepsy. Second, is it possible to mimic the mechanisms of action of ketogenic dietary therapy with a drug (eg, a tablet formulation)? A third controversy worthy of future study involves its expanded usage in adults with refractory epilepsy and its role in treating women of childbearing age.",
keywords = "diet, epilepsy, fasting, ketogenic, ketosis",
author = "Eric Kossoff and Mackenzie Cervenka",
note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Dr Kossoff has received royalties from Demos Health, Oxford Press, and UpToDate. Dr. Cervenka has received grant support from Nutricia, Vitaflo, Army Research Laboratory, The William and Ella Owens Medical Research Foundation, and BrightFocus Foundation. Dr. Cervenka receives speaking honoraria from LivaNova, Epigenix, Nutricia and the Glut1 Deficiency Foundation and receives Royalties from Demos Health. Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Dr Kossoff has received royalties from Demos Health, Oxford Press, and UpToDate. Dr. Cervenka has received grant support from Nutricia, Vitaflo, Army Research Laboratory, The William and Ella Owens Medical Research Foundation, and BrightFocus Foundation. Dr. Cervenka receives speaking honoraria from LivaNova, Epigenix, Nutricia and the Glut1 Deficiency Foundation and receives Royalties from Demos Health. Publisher Copyright: {\textcopyright} The Author(s) 2019.",
year = "2020",
month = may,
day = "1",
doi = "10.1177/1535759719890337",
language = "English (US)",
volume = "20",
pages = "125--129",
journal = "Epilepsy Currents",
issn = "1535-7597",
publisher = "American Epilepsy Society",
number = "3",
}