Keratoplasty and Glaucoma

Annie M. Wu, Joshua D. Stein, Peter J. McDonnell, Paul P. Lee

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Factors contributing to postkeratoplasty glaucoma include the presence of preexisting glaucoma, the nature of the underlying condition precipitating corneal transplantation, disruption of aqueous outflow from the keratoplasty, and the use of corticosteroids to maintain graft clarity. Various medical, laser, and incisional surgical treatments can be used to treat glaucoma associated with keratoplasty; the impact of these interventions on graft clarity and graft survival is as important to patients as their effectiveness at lowering intraocular pressure, since keratoplasty is often performed to increase and maintain visual function. With trends toward increasing utilization of lamellar keratoplasty and the introduction of keratoprostheses, more research is needed to better understand the risk of glaucoma associated with these newer corneal surgeries and ways to effectively limit glaucomatous progression. Ultimately, continued advances in corneal transplantation techniques coupled with innovative medical and surgical options for lowering intraocular pressure will permit patients to better achieve graft clarity and maintain control of glaucoma following corneal transplantation, resulting in improved outcomes.

Original languageEnglish (US)
Title of host publicationAlbert and Jakobiec's Principles and Practice of Ophthalmology
Subtitle of host publicationFourth Edition
PublisherSpringer International Publishing
Pages2287-2330
Number of pages44
ISBN (Electronic)9783030426347
ISBN (Print)9783030426330
DOIs
StatePublished - Jan 1 2022

Keywords

  • Corneal transplant
  • Endothelial keratoplasty
  • Glaucoma
  • Graft failure
  • Intraocular pressure
  • Keratoplasty
  • Keratoprosthesis
  • Penetrating keratoplasty

ASJC Scopus subject areas

  • General Medicine

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