Journal search and commentary: Introduction

TY - JOUR

T1 - Journal search and commentary

T2 - Introduction

AU - Allen, Richard P.

AU - Sanders, Mark H.

N1 - Funding Information: Funding for this study was provided by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. No grant number is applicable. Funding Information: The authors thank Maxine Giannotti and Cathie Scalzo for study support, Scott Diede and Scot Ebbinghaus for study design and oversight, and Andrea L. Webber, Michael Nebozhyn (all from Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA), and Robin Mogg for assistance with biomarker analyses. Medical writing and/or editorial assistance was provided by Doyel Mitra, PhD, and Cathy Winter, PhD of the ApotheCom pembrolizumab team (Yardley, PA). This assistance was funded by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. This research was funded in part through the NIH/NCI Cancer Center Support Grant P30 CA0087 48. Funding for this research was provided by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. Funding Information: The authors thank Maxine Giannotti and Cathie Scalzo for study support, Scott Diede and Scot Ebbinghaus for study design and oversight, and Andrea L. Webber, Michael Nebozhyn (all from Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA), and Robin Mogg for assistance with biomarker analyses. Medical writing and/or editorial assistance was provided by Doyel Mitra, PhD, and Cathy Winter, PhD of the ApotheCom pembrolizumab team (Yardley, PA). This assistance was funded by Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA. This research was funded in part through the NIH/NCI Cancer Center Support Grant P30 CA0087 48. Funding for this research was provided by Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA. Data availability: The Merck & Co. Inc. data sharing policy, including restrictions, is available at http://engagezone.merck.com/ds_documentation.php. Requests for access to the study data can be submitted through the EngageZone site or via email to dataaccess@merck.com. Funding for this study was provided by Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA. No grant number is applicable. Funding for this study was provided by Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA; no grant number is applicable. The sponsor collaborated with academic advisers to design the study and gather, analyze, and interpret the results. All authors had full access to all study data and approved the decision to submit the manuscript for publication. OH reports personal fees from Merck, during the conduct of the study; personal fees from Amgen, Novartis, Genentech Roche, BMS, and Array Biopharma; and other support from Astra Zeneca, BMS, Celldex, Genentech Roche, lmmunocore, lncyte, Merck, Merck Sereno, Medlmmune, Novartis, Pfizer, and Rinat outside the submitted work. CR reports personal fees from BMS, Pierre Fabre, Novartis, Amgen, Merck, and Roche, outside the submitted work. AD reports grants and personal fees from Merck, BMS, personal fees from Amgen, and grants from Incyte, during the conduct of the study. FSH reports clinical trial support to the institution from BMS during the conduct of the study; grants to the institution and personal fees from BMS, and personal fees from Merck, EMD Serono, Novartis, Celldex, Amgen, Genentech/Roche, Incyte, Apricity, Bayer, Aduro, Partners Therapeutics, Sanofi, Pfizer, Pionyr, Seven Hills Pharma, Verastern, Compass Therapeutics, Takeda, and Surface, outside the submitted work. FSH has received personal fees from and holds equity in Torque. FSH holds a patent pending with royalties paid for Methods for Testing MICA Related Disorders (#20100111973), issued patents Tumor antigens and uses thereof (#7250291), and Therapeutic Peptides (#9402905); and patents pending for Angiopoiten-2 Biomarkers Predictive of Anti-immune checkpoint response (#20170248603), Compositions and Methods for Identification, Assessment, Prevention, and Treatment of Melanoma using PD-L1 Isoforms (#20160340407), Therapeutic Peptides (#20160046716, #20140004112, #20170022275, #20170008962), and Methods of Using Pembrolizumab and Trebananib (#Pending). RK reports other support from Merck during the conduct of the study and other support from BMS, Novartis, Amgen, and Teva outside the submitted work. JDW reports grants and personal fees from Merck during the conduct of the study; personal fees from and stock ownership in BeiGene, Apricity, and Adaptive Biotech; is the cofounder of, has stock ownership in, and has received personal fees from Potenza, Tizona, Imvaq, and Trieza; grants and personal fees from BMS, Genetech, MedImmune, and personal fees from Surface Oncology, Polaris, Polonoma, Array BioPharma, Ascentage, Chugai, FStar, Sellas Life Sciences, Serametrix, Neon, Eli Lilly, Kleo, Psioxus, Syndax, Recepta, Amgen, Puretech, Elucida, Ono, and Celgene outside the submitted work. JDW holds patents and receives royalties for Xenogeneic DNA vaccines, anti-CTLA4 antibodies, and anti-GITR antibodies and methods of use thereof. JDW has patents pending for Alphavirus, NewCastle Disease Viruses for Cancer Therapy, Genomic Signature to Identify Responders to Ipilimumab in Melanoma, Engineered Vaccinia Viruses for Cancer Immunotherapy, Anti-CD40 agonist mAb fused to Monophosphoryl Lipid A (MPL) for cancer therapy, and CAR+ T cells targeting differentiation antigens as means to treat cancer. RJ reports other support from Merck as a consultant outside the submitted work. JSW reports personal fees from Merck, BMS, Genentech, Celldex, Pfizer, and AstraZeneca outside the submitted work. In addition, JSW is named on a PD-1 biomarker patent issued by Biodesix. TCM reports personal fees from BMS, Aduro, Merck, and lncyte, outside the submitted work. AP reports grants from Merck during the conduct of the study. HZ reports grants from BMS, Merck, Tesaro, and Imcheck outside the submitted work. QZ, EJ, and SA are employees of Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA. NI is an employee and stockholder of Merck Sharp & Dohme Corp. a subsidiary of Merck & Co. Inc. Kenilworth, NJ, USA, and a stockholder of GlaxoSmithKline. AR reports financial support from Merck for the conduct of the clinical trial through an institutional contract with UCLA, during the conduct of the study and personal fees from Merck outside the submitted work. WJH, PH, RD, and AJ have nothing to disclose. Merck & Co., Merck Sharp & Dohme Corp., Inc., Merck Sharp & Dohme Corp. Funding Information: OH reports personal fees from Merck, during the conduct of the study; personal fees from Amgen, Novartis, Genentech Roche, BMS, and Array Biopharma; and other support from Astra Zeneca, BMS, Celldex, Genentech Roche, lmmunocore, lncyte, Merck, Merck Sereno, Medlmmune, Novartis, Pfizer, and Rinat outside the submitted work. CR reports personal fees from BMS, Pierre Fabre, Novartis, Amgen, Merck, and Roche, outside the submitted work. AD reports grants and personal fees from Merck, BMS, personal fees from Amgen, and grants from Incyte, during the conduct of the study. FSH reports clinical trial support to the institution from BMS during the conduct of the study; grants to the institution and personal fees from BMS, and personal fees from Merck, EMD Serono, Novartis, Celldex, Amgen, Genentech/Roche, Incyte, Apricity, Bayer, Aduro, Partners Therapeutics, Sanofi, Pfizer, Pionyr, Seven Hills Pharma, Verastern, Compass Therapeutics, Takeda, and Surface, outside the submitted work. FSH has received personal fees from and holds equity in Torque. FSH holds a patent pending with royalties paid for Methods for Testing MICA Related Disorders (#20100111973), issued patents Tumor antigens and uses thereof (#7250291), and Therapeutic Peptides (#9402905); and patents pending for Angiopoiten-2 Biomarkers Predictive of Anti-immune checkpoint response (#20170248603), Compositions and Methods for Identification, Assessment, Prevention, and Treatment of Melanoma using PD-L1 Isoforms (#20160340407), Therapeutic Peptides (#20160046716, #20140004112, #20170022275, #20170008962), and Methods of Using Pembrolizumab and Trebananib (#Pending). RK reports other support from Merck during the conduct of the study and other support from BMS, Novartis, Amgen, and Teva outside the submitted work. JDW reports grants and personal fees from Merck during the conduct of the study; personal fees from and stock ownership in BeiGene, Apricity, and Adaptive Biotech; is the cofounder of, has stock ownership in, and has received personal fees from Potenza, Tizona, Imvaq, and Trieza; grants and personal fees from BMS, Genetech, MedImmune, and personal fees from Surface Oncology, Polaris, Polonoma, Array BioPharma, Ascentage, Chugai, FStar, Sellas Life Sciences, Serametrix, Neon, Eli Lilly, Kleo, Psioxus, Syndax, Recepta, Amgen, Puretech, Elucida, Ono, and Celgene outside the submitted work. JDW holds patents and receives royalties for Xenogeneic DNA vaccines, anti-CTLA4 antibodies, and anti-GITR antibodies and methods of use thereof. JDW has patents pending for Alphavirus, NewCastle Disease Viruses for Cancer Therapy, Genomic Signature to Identify Responders to Ipilimumab in Melanoma, Engineered Vaccinia Viruses for Cancer Immunotherapy, Anti-CD40 agonist mAb fused to Monophosphoryl Lipid A (MPL) for cancer therapy, and CAR+ T cells targeting differentiation antigens as means to treat cancer. RJ reports other support from Merck as a consultant outside the submitted work. JSW reports personal fees from Merck, BMS, Genentech, Celldex, Pfizer, and AstraZeneca outside the submitted work. In addition, JSW is named on a PD-1 biomarker patent issued by Biodesix. TCM reports personal fees from BMS, Aduro, Merck, and lncyte, outside the submitted work. AP reports grants from Merck during the conduct of the study. HZ reports grants from BMS, Merck, Tesaro, and Imcheck outside the submitted work. QZ, EJ, and SA are employees of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. NI is an employee and stockholder of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA, and a stockholder of GlaxoSmithKline. AR reports financial support from Merck for the conduct of the clinical trial through an institutional contract with UCLA, during the conduct of the study and personal fees from Merck outside the submitted work. WJH, PH, RD, and AJ have nothing to disclose.

PY - 2003/1

Y1 - 2003/1

UR - http://www.scopus.com/inward/record.url?scp=0037216972&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037216972&partnerID=8YFLogxK

U2 - 10.1016/s1389-9457(02)00246-0

DO - 10.1016/s1389-9457(02)00246-0

M3 - Editorial

AN - SCOPUS:0037216972

SN - 1389-9457

VL - 4

SP - 79

JO - Sleep Medicine

JF - Sleep Medicine

IS - 1

ER -