@inbook{c352237ec2d349f8b95c9a0390bae15f,
title = "Isolation of Kinetoplast DNA",
abstract = "The kinetoplast DNA (kDNA) network of the protozoan parasite Crithidia fasciculata is a naturally occurring gigantic catenane containing several thousand DNA minicircles. Because of its unusual structure, kDNA is an excellent substrate to use in decatenation assays of topoisomerase activity. Beyond this application, kDNA has also proven a fascinating experimental subject in its own right. Studies of the unique structure, mechanism of replication, and genetic function of kDNA have led to numerous interesting discoveries (seerefs.1-5 for reviews).",
keywords = "Beckman SW28 Rotor, CsCl Gradient, Gentian Violet, Kinetoplastid Parasite, Sucrose Cushion",
author = "Shapiro, {Theresa A.} and Klein, {Viiu A.} and Englund, {Paul T.}",
note = "Funding Information: This work was supported by grants from the National Institutes of Health (GM-27608 and AI-28855) and from the Burroughs Wellcome Fund. Publisher Copyright: {\textcopyright} 1999, Humana Press Inc.",
year = "1999",
doi = "10.1385/1-59259-259-7:61",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "61--67",
booktitle = "Methods in Molecular Biology",
}