Isolated oculomotor nerve palsy in childhood from leptomeningeal polymorphic cell sarcoma

N. R. Miller

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1 Scopus citations


Solitary third nerve palsy is an infrequent neurological sign in children. It is usually encountered as a congenital lesion or as a result of head injury or infection. In rare instances it has been reported as the presenting sign of intracranial aneurysm and pituitary adenoma. The syndrome of ophthalmoplegic migraine may begin at an early age with transient but complete third nerve palsy, and a total third nerve palsy has been documented in infants prior to development of cyclic oculomotor paralysis. Although intracranial tumors in children can cause third nerve palsy by effects of elevated intracranial pressure with hippocampal herniation or by direct infiltration by malignant cells, such a palsy is rarely the first sign. This report describes a case of a young boy in whom a unilateral, complete third nerve palsy occurred suddenly, and persisted for six months before other signs and symptoms led to discovery of a diffuse, leptomeningeal polymorphic cell sarcoma.

Original languageEnglish (US)
Pages (from-to)211-214
Number of pages4
JournalJournal of Pediatric Ophthalmology
Issue number4
StatePublished - Dec 1 1976

ASJC Scopus subject areas

  • General Medicine


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